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Bioinformatics-Guided Discovery of Biaryl-Tailored Lasso Peptides

Lasso peptides are a class of ribosomally synthesized and post-translationally modified peptides (RiPPs) that feature an isopeptide bond and a distinct lariat fold. A growing number of secondary modifications have been described that further decorate lasso peptide scaffolds. Using genome mining, we...

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Detalles Bibliográficos
Autores principales: Saad, Hamada, Majer, Thomas, Bhattarai, Keshab, Lampe, Sarah, Nguyen, Dinh T., Kramer, Markus, Straetener, Jan, Brötz-Oesterhelt, Heike, Mitchell, Douglas A., Gross, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028836/
https://www.ncbi.nlm.nih.gov/pubmed/36945544
http://dx.doi.org/10.1101/2023.03.06.531328