Cargando…

Disruption of Golgi markers by two RILP-directed shRNAs in neurons: a new role for RILP or a neuron-specific off-target phenotype?

In neurons, degradation of dendritic cargos requires RAB7 and dynein-mediated retrograde transport to somatic lysosomes. In order to test if the dynein adaptor RILP (RAB-interacting lysosomal protein) mediated the recruitment of dynein to late endosomes for retrograde transport in dendrites, we obta...

Descripción completa

Detalles Bibliográficos
Autores principales: Yap, Chan Choo, Digilio, Laura, McMahon, Lloyd, Winckler, Bettina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028860/
https://www.ncbi.nlm.nih.gov/pubmed/36945482
http://dx.doi.org/10.1101/2023.03.08.531742