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Disruption of Golgi markers by two RILP-directed shRNAs in neurons: a new role for RILP or a neuron-specific off-target phenotype?

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In neurons, degradation of dendritic cargos requires RAB7 and dynein-mediated retrograde transport to somatic lysosomes. In order to test if the dynein adaptor RILP (RAB-interacting lysosomal protein) mediated the recruitment of dynein to late endosomes for retrograde transport in dendrites, we obta...

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Detalles Bibliográficos
Autores principales:	Yap, Chan Choo, Digilio, Laura, McMahon, Lloyd, Winckler, Bettina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028860/ https://www.ncbi.nlm.nih.gov/pubmed/36945482 http://dx.doi.org/10.1101/2023.03.08.531742

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