Microglial MHC-I induction with aging and Alzheimer’s is conserved in mouse models and humans

Major Histocompatibility Complex I (MHC-I) CNS cellular localization and function is still being determined after previously being thought to be absent from the brain. MHC-I expression has been reported to increase with brain aging in mouse, rat, and human whole tissue analyses but the cellular loca...

Descripción completa

Detalles Bibliográficos
Autores principales: Kellogg, Collyn M., Pham, Kevin, Machalinski, Adeline H., Porter, Hunter L., Blankenship, Harris E., Tooley, Kyla, Stout, Michael B., Rice, Heather C., Sharpe, Amanda L., Beckstead, Michael J., Chucair-Elliott, Ana J., Ocañas, Sarah R., Freeman, Willard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028873/
https://www.ncbi.nlm.nih.gov/pubmed/36945372
http://dx.doi.org/10.1101/2023.03.07.531435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028873/
https://www.ncbi.nlm.nih.gov/pubmed/36945372
http://dx.doi.org/10.1101/2023.03.07.531435

Ejemplares similares