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Massively parallel characterization of transcriptional regulatory elements in three diverse human cell types

The human genome contains millions of candidate cis-regulatory elements (CREs) with cell-type-specific activities that shape both health and myriad disease states. However, we lack a functional understanding of the sequence features that control the activity and cell-type-specific features of these...

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Detalles Bibliográficos
Autores principales: Agarwal, Vikram, Inoue, Fumitaka, Schubach, Max, Martin, Beth K., Dash, Pyaree Mohan, Zhang, Zicong, Sohota, Ajuni, Noble, William Stafford, Yardimci, Galip Gürkan, Kircher, Martin, Shendure, Jay, Ahituv, Nadav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028905/
https://www.ncbi.nlm.nih.gov/pubmed/36945371
http://dx.doi.org/10.1101/2023.03.05.531189