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Accurate modeling of peptide-MHC structures with AlphaFold

Major histocompatibility complex (MHC) proteins present peptides on the cell surface for T-cell surveillance. Reliable in silico prediction of which peptides would be presented and which T-cell receptors would recognize them is an important problem in structural immunology. Here, we introduce an Alp...

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Detalles Bibliográficos
Autores principales: Mikhaylov, Victor, Levine, Arnold J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028922/
https://www.ncbi.nlm.nih.gov/pubmed/36945436
http://dx.doi.org/10.1101/2023.03.06.531396