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Quantifying tumor specificity using Bayesian probabilistic modeling for drug target discovery and prioritization
In diseases such as cancer, the design of new therapeutic strategies requires extensive, costly, and unfortunately sometimes deadly testing to reveal life threatening “off target” effects. A crucial first step in predicting toxicity are analyses of normal RNA and protein tissue expression, which are...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028977/ https://www.ncbi.nlm.nih.gov/pubmed/36945433 http://dx.doi.org/10.1101/2023.03.03.530994 |