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Patterns of unwanted biological and technical expression variation across 49 human tissues

All tissue-based gene expression studies are impacted by biological and technical sources of variation. Numerous methods are used to normalize and batch correct these datasets. A more accurate understanding of all causes of variation could further optimize these approaches. We used 17,282 samples fr...

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Detalles Bibliográficos
Autores principales: Nieuwenhuis, Tim O., Giles, Hunter H., McCall, Matthew N., Halushka, Marc K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028996/
https://www.ncbi.nlm.nih.gov/pubmed/36945408
http://dx.doi.org/10.1101/2023.03.09.531935