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Pharmacogenetics of SGLT2 Inhibitors: Validation of a sex-agnostic pharmacodynamic biomarker

AIM: SGLT2 inhibitors provide multiple benefits to patients with type 2 diabetes – including improved glycemic control and decreased risks of cardiorenal disease. Because drug responses vary among individuals, we initiated investigations to identify genetic variants associated with the magnitude of...

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Detalles Bibliográficos
Autores principales: Taylor, Simeon I., Cherng, Hua-Ren, Yazdi, Zhinous Shahidzadeh, Montasser, May E., Whitlatch, Hilary B., Mitchell, Braxton D., Shuldiner, Alan R., Streeten, Elizabeth A., Beitelshees, Amber L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029014/
https://www.ncbi.nlm.nih.gov/pubmed/36945579
http://dx.doi.org/10.1101/2023.03.07.23286875