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Resolving the soluble-to-toxic transformation of amyloidogenic proteins: A method to assess intervention by small-molecules
The soluble-to-toxic transformation of intrinsically disordered amyloidogenic proteins such as amyloid beta (Aβ), α-synuclein, mutant Huntingtin Protein (mHTT) and islet amyloid polypeptide (IAPP) among others is associated with disorders such as Alzheimer’s disease (AD), Parkinson’s disease (PD), H...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Journal Experts
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029074/ https://www.ncbi.nlm.nih.gov/pubmed/36945382 http://dx.doi.org/10.21203/rs.3.rs-2631727/v1 |