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An animal-free preclinical drug screening platform based on human precision-cut kidney slices

OBJECTIVE: Renal fibrosis is one of the main pathophysiological processes underlying the progression of chronic kidney disease and kidney allograft failure. In the past decades, overwhelming efforts have been undertaken to find druggable targets for the treatment of renal fibrosis, mainly using cell...

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Detalles Bibliográficos
Autores principales: Mutsaers, Henricus A. M., Jensen, Michael Schou, Kresse, Jean-Claude, Tingskov, Stine Julie, Madsen, Mia Gebauer, Nørregaard, Rikke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029185/
https://www.ncbi.nlm.nih.gov/pubmed/36941637
http://dx.doi.org/10.1186/s13104-023-06303-4