Inflammasome inhibition protects dopaminergic neurons from α-synuclein pathology in a model of progressive Parkinson’s disease

Neuroinflammation has been suggested as a pathogenetic mechanism contributing to Parkinson’s disease (PD). However, anti-inflammatory treatment strategies have not yet been established as a therapeutic option for PD patients. We have used a human α-synuclein mouse model of progressive PD to examine...

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Detalles Bibliográficos
Autores principales: Grotemeyer, Alexander, Fischer, Judith F., Koprich, James B., Brotchie, Jonathan M., Blum, Robert, Volkmann, Jens, Ip, Chi Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029189/
https://www.ncbi.nlm.nih.gov/pubmed/36945016
http://dx.doi.org/10.1186/s12974-023-02759-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029189/
https://www.ncbi.nlm.nih.gov/pubmed/36945016
http://dx.doi.org/10.1186/s12974-023-02759-0

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