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DNA methylation abnormalities induced by advanced maternal age in villi prime a high-risk state for spontaneous abortion
BACKGROUND: Advanced maternal age (AMA) has increased in many high-income countries in recent decades. AMA is generally associated with a higher risk of various pregnancy complications, and the underlying molecular mechanisms are largely unknown. In the current study, we profiled the DNA methylome o...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029192/ https://www.ncbi.nlm.nih.gov/pubmed/36945044 http://dx.doi.org/10.1186/s13148-023-01432-w |