DNA methylation abnormalities induced by advanced maternal age in villi prime a high-risk state for spontaneous abortion

BACKGROUND: Advanced maternal age (AMA) has increased in many high-income countries in recent decades. AMA is generally associated with a higher risk of various pregnancy complications, and the underlying molecular mechanisms are largely unknown. In the current study, we profiled the DNA methylome o...

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Detalles Bibliográficos
Autores principales: Qin, Meng, Chen, Wei, Hua, Lingyue, Meng, Yan, Wang, Jing, Li, Hanna, Yang, Rui, Yan, Liying, Qiao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029192/
https://www.ncbi.nlm.nih.gov/pubmed/36945044
http://dx.doi.org/10.1186/s13148-023-01432-w

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