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Perinatal tissue-derived exosomes ameliorate colitis in mice by regulating the Foxp3 + Treg cells and gut microbiota

BACKGROUND: The capacity of self-renewal and multipotent differentiation makes mesenchymal stem cells (MSC) one of the most widely investigated cell lines in preclinical studies as cell-based therapies. However, the low survival rate and poor homing efficiency of MSCs after transplantation hinder th...

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Detalles Bibliográficos
Autores principales: Yan, Yaping, Li, Kaixiu, Jiang, Jiang, Jiang, Lihong, Ma, Xiang, Ai, Fang, Qiu, Shuai, Si, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029206/
https://www.ncbi.nlm.nih.gov/pubmed/36941715
http://dx.doi.org/10.1186/s13287-023-03263-1