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Identification of kukoamine a as an anti-osteoporosis drug target using network pharmacology and experiment verification

BACKGROUND: Osteoporosis (OP) is a major and growing public health problem characterized by decreased bone mineral density and destroyed bone microarchitecture. Previous studies found that Lycium Chinense Mill (LC) has a potent role in inhibiting bone loss. Kukoamine A (KuA), a bioactive compound ex...

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Detalles Bibliográficos
Autores principales: Luo, Liying, Guan, Zhiyuan, Jin, Xiao, Guan, Zhiqiang, Jiang, Yanyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029210/
https://www.ncbi.nlm.nih.gov/pubmed/36941586
http://dx.doi.org/10.1186/s10020-023-00625-6