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Identification of kukoamine a as an anti-osteoporosis drug target using network pharmacology and experiment verification
BACKGROUND: Osteoporosis (OP) is a major and growing public health problem characterized by decreased bone mineral density and destroyed bone microarchitecture. Previous studies found that Lycium Chinense Mill (LC) has a potent role in inhibiting bone loss. Kukoamine A (KuA), a bioactive compound ex...
Autores principales: | Luo, Liying, Guan, Zhiyuan, Jin, Xiao, Guan, Zhiqiang, Jiang, Yanyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029210/ https://www.ncbi.nlm.nih.gov/pubmed/36941586 http://dx.doi.org/10.1186/s10020-023-00625-6 |
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