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Human umbilical cord mesenchymal stem cells conditioned medium exerts anti-tumor effects on KGN cells in a cell density-dependent manner through activation of the Hippo pathway

BACKGROUND: The conditioned medium from human umbilical cord mesenchymal stem cells (UCMSCs-CM) provides a new cell-free therapy for tumors due to its unique secretome. However, there are many contradictory reports about the effect of UCMSCs-CM on tumor cells. The loss of contact inhibition is a com...

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Detalles Bibliográficos
Autores principales: Wan, Wenjing, Miao, Yuyang, Niu, Yuwei, Zhu, Kunyuan, Ma, Yingwan, Pan, Menghao, Ma, Baohua, Wei, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029233/
https://www.ncbi.nlm.nih.gov/pubmed/36941685
http://dx.doi.org/10.1186/s13287-023-03273-z