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Aging aggravates acetaminophen-induced acute liver injury and inflammation through inordinate C/EBPα-BMP9 crosstalk

BACKGROUND: Previous studies have shown that bone morphogenetic protein 9 (BMP9) is almost exclusively produced in the liver and reaches tissues throughout the body as a secreted protein. However, the mechanism of BMP9 action and its role in aging-associated liver injury and inflammation are still u...

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Detalles Bibliográficos
Autores principales: Liu, Rui, Xu, Wentao, Zhu, He, Dong, Zijian, Dong, Huke, Yin, Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029235/
https://www.ncbi.nlm.nih.gov/pubmed/36945064
http://dx.doi.org/10.1186/s13578-023-01014-6