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Exosomal Lnc NEAT1 from endothelial cells promote bone regeneration by regulating macrophage polarization via DDX3X/NLRP3 axis

BACKGROUND: Bone regeneration is a complex procedure that involves an interaction between osteogenesis and inflammation. Macrophages in the microenvironment are instrumental in bone metabolism. Amount evidence have revealed that exosomes transmitting lncRNA is crucial nanocarriers for cellular inter...

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Detalles Bibliográficos
Autores principales: Chen, Yuxuan, Wu, Yuanhao, Guo, Linlin, Yuan, Shijie, Sun, Jiaming, Zhao, Kangcheng, Wang, Jiecong, An, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029245/
https://www.ncbi.nlm.nih.gov/pubmed/36941678
http://dx.doi.org/10.1186/s12951-023-01855-w