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Conformational Behavior of SARS-Cov-2 Spike Protein Variants: Evolutionary Jumps in Sequence Reverberate in Structural Dynamic Differences

[Image: see text] SARS-CoV-2 has evolved rapidly in the first 3 years of pandemic diffusion. The initial evolution of the virus appeared to proceed through big jumps in sequence changes rather than through the stepwise accumulation of point mutations on already established variants. Here, we examine...

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Detalles Bibliográficos
Autores principales: Triveri, Alice, Casali, Emanuele, Frasnetti, Elena, Doria, Filippo, Frigerio, Francesco, Cinquini, Fabrizio, Pavoni, Silvia, Moroni, Elisabetta, Marchetti, Filippo, Serapian, Stefano A., Colombo, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029694/
https://www.ncbi.nlm.nih.gov/pubmed/36926878
http://dx.doi.org/10.1021/acs.jctc.3c00077