Aim2 Deficiency Ameliorates Lacrimal Gland Destruction and Corneal Epithelium Defects in an Experimental Dry Eye Model

PURPOSE: Dry eye disease (DED) is a multifactorial disease that is associated with inflammation. Excessive DNA is present in the tear fluid of patients with DED. Absent in melanoma 2 (AIM2) is a key DNA sensor. This study aimed to investigate the role of AIM2 in the pathogenesis of DED. METHODS: DED...

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Detalles Bibliográficos
Autores principales: Chen, Yu, Pu, Jiheng, Li, Xinda, Lian, Lili, Ge, Chaoxiang, Liu, Zuimeng, Wang, Weizhuo, Hou, Ling, Chen, Wei, Li, Jinyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029764/
https://www.ncbi.nlm.nih.gov/pubmed/36920364
http://dx.doi.org/10.1167/iovs.64.3.26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029764/
https://www.ncbi.nlm.nih.gov/pubmed/36920364
http://dx.doi.org/10.1167/iovs.64.3.26

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