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TIGAR Protects Cochlear Hair Cells against Teicoplanin-Induced Damage

Teicoplanin is a glycopeptide antibiotic used to treat severe staphylococcal infections. It has been claimed that teicoplanin possesses ototoxic potential, although its toxic effects on cochlear hair cells (HCs) remain unknown. The TP53-induced glycolysis and apoptosis regulator (TIGAR) plays a cruc...

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Detalles Bibliográficos
Autores principales: Zhang, Qiongmin, Yao, Zhiqun, Chen, Fang, Wang, Xue, Wang, Man, Lu, Junze, Meng, Yu, Xu, Lei, Han, Yuechen, Liu, Wenwen, Wang, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10029784/
https://www.ncbi.nlm.nih.gov/pubmed/36943624
http://dx.doi.org/10.1007/s12035-023-03309-8