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Osteosarcoma-enriched transcripts paradoxically generate osteosarcoma-suppressing extracellular proteins

Osteosarcoma (OS) is the common primary bone cancer that affects mostly children and young adults. To augment the standard-of-care chemotherapy, we examined the possibility of protein-based therapy using mesenchymal stem cells (MSCs)-derived proteomes and OS-elevated proteins. While a conditioned me...

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Detalles Bibliográficos
Autores principales: Li, Kexin, Huo, Qingji, Dimmitt, Nathan H, Qu, Guofan, Bao, Junjie, Pandya, Pankita H, Saadatzadeh, M Reza, Bijangi-Vishehsaraei, Khadijeh, Kacena, Melissa A, Pollok, Karen E, Lin, Chien-Chi, Li, Bai-Yan, Yokota, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030111/
https://www.ncbi.nlm.nih.gov/pubmed/36943734
http://dx.doi.org/10.7554/eLife.83768