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Surfaceome mapping of primary human heart cells with CellSurfer uncovers cardiomyocyte surface protein LSMEM2 and proteome dynamics in failing hearts

Cardiac cell surface proteins are drug targets and useful biomarkers for discriminating among cellular phenotypes and disease states. Here we developed an analytical platform, CellSurfer, that enables quantitative cell surface proteome (surfaceome) profiling of cells present in limited quantities, a...

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Detalles Bibliográficos
Autores principales: Luecke, Linda Berg, Waas, Matthew, Littrell, Jack, Wojtkiewicz, Melinda, Castro, Chase, Burkovetskaya, Maria, Schuette, Erin N., Buchberger, Amanda Rae, Churko, Jared M., Chalise, Upendra, Waknitz, Michelle, Konfrst, Shelby, Teuben, Roald, Morrissette-McAlmon, Justin, Mahr, Claudius, Anderson, Daniel R., Boheler, Kenneth R., Gundry, Rebekah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030153/
https://www.ncbi.nlm.nih.gov/pubmed/36950336
http://dx.doi.org/10.1038/s44161-022-00200-y