Calcineurin Signalling in Astrocytes: From Pathology to Physiology and Control of Neuronal Functions

Calcineurin (CaN), a Ca(2+)/calmodulin-activated serine/threonine phosphatase, acts as a Ca(2+)-sensitive switch regulating cellular functions through protein dephosphorylation and activation of gene transcription. In astrocytes, the principal homeostatic cells in the CNS, over-activation of CaN is...

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Detalles Bibliográficos
Autores principales: Lim, Dmitry, Tapella, Laura, Dematteis, Giulia, Talmon, Maria, Genazzani, Armando A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030417/
https://www.ncbi.nlm.nih.gov/pubmed/36083398
http://dx.doi.org/10.1007/s11064-022-03744-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030417/
https://www.ncbi.nlm.nih.gov/pubmed/36083398
http://dx.doi.org/10.1007/s11064-022-03744-4

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