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Calcineurin Signalling in Astrocytes: From Pathology to Physiology and Control of Neuronal Functions
Calcineurin (CaN), a Ca(2+)/calmodulin-activated serine/threonine phosphatase, acts as a Ca(2+)-sensitive switch regulating cellular functions through protein dephosphorylation and activation of gene transcription. In astrocytes, the principal homeostatic cells in the CNS, over-activation of CaN is...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030417/ https://www.ncbi.nlm.nih.gov/pubmed/36083398 http://dx.doi.org/10.1007/s11064-022-03744-4 |