Oral formulation of bendamustine hydrochloride for patients with advanced solid tumors; a phase 1 study

To determine the maximum tolerated dose (MTD) and recommended dose (RD) of orally-administered bendamustine in Japanese patients with advanced solid tumors. The optimal dosing schedule, safety, pharmacokinetics, and preliminary antitumor effects were also evaluated. A multicenter, open-label trial w...

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Detalles Bibliográficos
Autores principales: Shimizu, Toshio, Nakagawa, Kazuhiko, Hayashi, Hidetoshi, Iwasa, Tsutomu, Kawakami, Hisato, Watanabe, Satomi, Yamamoto, Noboru, Yonemori, Kan, Koyama, Takafumi, Sato, Jun, Tamura, Kenji, Kikuchi, Keiichi, Akaike, Kenichiro, Takeda, Shiho, Takeda, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030450/
https://www.ncbi.nlm.nih.gov/pubmed/36331674
http://dx.doi.org/10.1007/s10637-022-01307-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030450/
https://www.ncbi.nlm.nih.gov/pubmed/36331674
http://dx.doi.org/10.1007/s10637-022-01307-6

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