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Oral formulation of bendamustine hydrochloride for patients with advanced solid tumors; a phase 1 study

To determine the maximum tolerated dose (MTD) and recommended dose (RD) of orally-administered bendamustine in Japanese patients with advanced solid tumors. The optimal dosing schedule, safety, pharmacokinetics, and preliminary antitumor effects were also evaluated. A multicenter, open-label trial w...

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Detalles Bibliográficos
Autores principales:	Shimizu, Toshio, Nakagawa, Kazuhiko, Hayashi, Hidetoshi, Iwasa, Tsutomu, Kawakami, Hisato, Watanabe, Satomi, Yamamoto, Noboru, Yonemori, Kan, Koyama, Takafumi, Sato, Jun, Tamura, Kenji, Kikuchi, Keiichi, Akaike, Kenichiro, Takeda, Shiho, Takeda, Masayuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030450/ https://www.ncbi.nlm.nih.gov/pubmed/36331674 http://dx.doi.org/10.1007/s10637-022-01307-6

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