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Trial-of-antibiotics to assist tuberculosis diagnosis in symptomatic adults in Malawi (ACT-TB study): a randomised controlled trial

BACKGROUND: Clinical practice and diagnostic algorithms often assume that tuberculosis can be ruled out in mycobacteriology-negative individuals whose symptoms improve with a trial-of-antibiotics. We aimed to investigate diagnostic performance, clinical benefit, and antimicrobial resistance using a...

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Detalles Bibliográficos
Autores principales: Divala, Titus H, Corbett, Elizabeth L, Kandulu, Chikondi, Moyo, Brewster, MacPherson, Peter, Nliwasa, Marriott, French, Neil, Sloan, Derek J, Chiume, Lingstone, Ndaferankhande, Masiye John, Chilanga, Sanderson, Majiga, Sabina Tazirwa, Odland, Jon Øyvind, Fielding, Katherine L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030459/
https://www.ncbi.nlm.nih.gov/pubmed/36925176
http://dx.doi.org/10.1016/S2214-109X(23)00052-9