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Structural basis for TRIM72 oligomerization during membrane damage repair

Tripartite Motif Protein 72 (TRIM72, also named MG53) mediates membrane damage repair through membrane fusion and exocytosis. During injury, TRIM72 molecules form intermolecular disulfide bonds in response to the oxidative environment and TRIM72 oligomers are proposed to connect vesicles to the plas...

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Detalles Bibliográficos
Autores principales: Ma, Yuemin, Ding, Lei, Li, Zhenhai, Zhou, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030467/
https://www.ncbi.nlm.nih.gov/pubmed/36944613
http://dx.doi.org/10.1038/s41467-023-37198-1