Cargando…

Sex differences in hippocampal β-amyloid accumulation in the triple-transgenic mouse model of Alzheimer’s disease and the potential role of local estrogens

INTRODUCTION: Epidemiological studies show that women have a higher prevalence of Alzheimer’s disease (AD) than men. Peripheral estrogen reduction during aging in women is proposed to play a key role in this sex-associated prevalence, however, the underlying mechanism remains elusive. We previously...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Yu-Ting, Chen, Xin-Lu, Zhang, Ya-Nan, McGurran, Hugo, Stormmesand, Jochem, Breeuwsma, Nicole, Sluiter, Arja, Zhao, Juan, Swaab, Dick, Bao, Ai-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030503/
https://www.ncbi.nlm.nih.gov/pubmed/36968493
http://dx.doi.org/10.3389/fnins.2023.1117584