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Surface roughness modulates EGFR signaling and stemness of triple-negative breast cancer cells

Introduction: Cancer stem cells (CSC), a major culprit of drug-resistant phenotypes and tumor relapse, represent less than 2 % of the bulk of TNBC cells, making them difficult to isolate, study, and thus, limiting our understanding of the pathogenesis of the disease. Current methods for CSC enrichme...

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Detalles Bibliográficos
Autores principales: Rosado-Galindo, Heizel, Domenech, Maribella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030610/
https://www.ncbi.nlm.nih.gov/pubmed/36968199
http://dx.doi.org/10.3389/fcell.2023.1124250