Pexidartinib synergize PD-1 antibody through inhibiting treg infiltration by reducing TAM-derived CCL22 in lung adenocarcinoma

There is a crosstalk between Tumor-associated macrophages (TAM) and tumor-infiltrating T cells in tumor environment. TAM could inhibit the activity of cytotoxic T cells; TAM could also regulate the composition of T cells in tumor immune environment. The combination therapy for TAM and tumor infiltra...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Jiang, Xi, Zou, Youcheng, Yuan, Lihua, Wang, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030616/
https://www.ncbi.nlm.nih.gov/pubmed/36969873
http://dx.doi.org/10.3389/fphar.2023.1092767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030616/
https://www.ncbi.nlm.nih.gov/pubmed/36969873
http://dx.doi.org/10.3389/fphar.2023.1092767

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