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Dynamic 3D imaging of cerebral blood flow in awake mice using self-supervised-learning-enhanced optical coherence Doppler tomography

Cerebral blood flow (CBF) is widely used to assess brain function. However, most preclinical CBF studies have been performed under anesthesia, which confounds findings. High spatiotemporal-resolution CBF imaging of awake animals is challenging due to motion artifacts and background noise, particular...

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Detalles Bibliográficos
Autores principales: Pan, Yingtian, Park, Kicheon, Ren, Jiaxiang, Volkow, Nora D., Ling, Haibin, Koretsky, Alan P., Du, Congwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030663/
https://www.ncbi.nlm.nih.gov/pubmed/36944712
http://dx.doi.org/10.1038/s42003-023-04656-x