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BHLHE22 drives the immunosuppressive bone tumor microenvironment and associated bone metastasis in prostate cancer

BACKGROUND: The molecular characteristics of prostate cancer (PCa) cells and the immunosuppressive bone tumor microenvironment (TME) contribute to the limitations of immune checkpoint therapy (ICT). Identifying subgroups of patients with PCa for ICT remains a challenge. Herein, we report that basic...

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Detalles Bibliográficos
Autores principales: Yin, Chi, Wang, Min, Wang, Yingzhao, Lin, Qijun, Lin, Kaiyuan, Du, Hong, Lang, Chuandong, Dai, Yuhu, Peng, Xinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030795/
https://www.ncbi.nlm.nih.gov/pubmed/36941015
http://dx.doi.org/10.1136/jitc-2022-005532