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HDAC2 as a target for developing anti-cancer drugs

Histone deacetylases (HDACs) deacetylate histones H3 and H4. An imbalance between histone acetylation and deacetylation can lead to various diseases. HDAC2 is present in the nucleus. It plays a critical role in modifying chromatin structures and regulates the expression of various genes by functioni...

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Detalles Bibliográficos
Autores principales: Jo, Hyein, Shim, Kyeonghee, Kim, Han-Ul, Jung, Hyun Suk, Jeoung, Dooil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030825/
https://www.ncbi.nlm.nih.gov/pubmed/36968022
http://dx.doi.org/10.1016/j.csbj.2023.03.016