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Cellular mechanisms of heterogeneity in NF2-mutant schwannoma

Schwannomas are common sporadic tumors and hallmarks of familial neurofibromatosis type 2 (NF2) that develop predominantly on cranial and spinal nerves. Virtually all schwannomas result from inactivation of the NF2 tumor suppressor gene with few, if any, cooperating mutations. Despite their genetic...

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Detalles Bibliográficos
Autores principales: Chiasson-MacKenzie, Christine, Vitte, Jeremie, Liu, Ching-Hui, Wright, Emily A., Flynn, Elizabeth A., Stott, Shannon L., Giovannini, Marco, McClatchey, Andrea I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030849/
https://www.ncbi.nlm.nih.gov/pubmed/36944680
http://dx.doi.org/10.1038/s41467-023-37226-0