Circulating tumor DNA: Opportunities and challenges for pharmacometric approaches

To support further development of model-informed drug development approaches leveraging circulating tumor DNA (ctDNA), we performed an exploratory analysis of the relationships between treatment-induced changes to ctDNA levels, clinical response and tumor size dynamics in patients with cancer treate...

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Detalles Bibliográficos
Autores principales: Ribba, Benjamin, Roller, Andreas, Helms, Hans-Joachim, Stern, Martin, Bleul, Conrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030934/
https://www.ncbi.nlm.nih.gov/pubmed/36968790
http://dx.doi.org/10.3389/fphar.2022.1058220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030934/
https://www.ncbi.nlm.nih.gov/pubmed/36968790
http://dx.doi.org/10.3389/fphar.2022.1058220

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