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Circulating tumor DNA: Opportunities and challenges for pharmacometric approaches

To support further development of model-informed drug development approaches leveraging circulating tumor DNA (ctDNA), we performed an exploratory analysis of the relationships between treatment-induced changes to ctDNA levels, clinical response and tumor size dynamics in patients with cancer treate...

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Detalles Bibliográficos
Autores principales:	Ribba, Benjamin, Roller, Andreas, Helms, Hans-Joachim, Stern, Martin, Bleul, Conrad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030934/ https://www.ncbi.nlm.nih.gov/pubmed/36968790 http://dx.doi.org/10.3389/fphar.2022.1058220

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