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Antiretroviral drugs efavirenz, dolutegravir and bictegravir dysregulate blood-brain barrier integrity and function

The implementation of combined antiretroviral therapy (cART) significantly reduces the mortality associated with human immunodeficiency virus (HIV) infection. However, complications such as HIV-associated neurocognitive disorders (HAND) remain a major health concern. We hypothesized that the toxicit...

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Detalles Bibliográficos
Autores principales: Huang, Chang, Hoque, Tozammel, Bendayan, Reina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10030948/
https://www.ncbi.nlm.nih.gov/pubmed/36969875
http://dx.doi.org/10.3389/fphar.2023.1118580