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Understanding the dosing-time-dependent antihypertensive effect of valsartan and aspirin through mathematical modeling
Chronopharmacology of arterial hypertension impacts the long-term cardiovascular risk of hypertensive subjects. Therefore, clinical and computational studies have proposed optimizing antihypertensive medications’ dosing time (Ta). However, the causes and mechanisms underlying the Ta-dependency antih...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031009/ https://www.ncbi.nlm.nih.gov/pubmed/36967780 http://dx.doi.org/10.3389/fendo.2023.1110459 |