Selective dysfunction of fast-spiking inhibitory interneurons and disruption of perineuronal nets in a tauopathy mouse model

In Alzheimer’s disease (AD), network hyperexcitability is frequently observed and associated with subsequent cognitive impairment. Dysfunction of inhibitory interneurons (INs) is thought to be one of the key biological mechanisms of hyperexcitability. However, it is still unknown how INs are functio...

Descripción completa

Detalles Bibliográficos
Autores principales: Kudo, Takehiro, Takuwa, Hiroyuki, Takahashi, Manami, Urushihata, Takuya, Shimojo, Masafumi, Sampei, Kazuaki, Yamanaka, Mitsugu, Tomita, Yutaka, Sahara, Naruhiko, Suhara, Tetsuya, Higuchi, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031157/
https://www.ncbi.nlm.nih.gov/pubmed/36968086
http://dx.doi.org/10.1016/j.isci.2023.106342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031157/
https://www.ncbi.nlm.nih.gov/pubmed/36968086
http://dx.doi.org/10.1016/j.isci.2023.106342

Ejemplares similares