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Selective dysfunction of fast-spiking inhibitory interneurons and disruption of perineuronal nets in a tauopathy mouse model

In Alzheimer’s disease (AD), network hyperexcitability is frequently observed and associated with subsequent cognitive impairment. Dysfunction of inhibitory interneurons (INs) is thought to be one of the key biological mechanisms of hyperexcitability. However, it is still unknown how INs are functio...

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Detalles Bibliográficos
Autores principales: Kudo, Takehiro, Takuwa, Hiroyuki, Takahashi, Manami, Urushihata, Takuya, Shimojo, Masafumi, Sampei, Kazuaki, Yamanaka, Mitsugu, Tomita, Yutaka, Sahara, Naruhiko, Suhara, Tetsuya, Higuchi, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031157/
https://www.ncbi.nlm.nih.gov/pubmed/36968086
http://dx.doi.org/10.1016/j.isci.2023.106342

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