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FkpA enhances membrane protein folding using an extensive interaction surface

Outer membrane protein (OMP) biogenesis in gram‐negative bacteria is managed by a network of periplasmic chaperones that includes SurA, Skp, and FkpA. These chaperones bind unfolded OMPs (uOMPs) in dynamic conformational ensembles to suppress aggregation, facilitate diffusion across the periplasm, a...

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Detalles Bibliográficos
Autores principales: Devlin, Taylor, Marx, Dagan C., Roskopf, Michaela A., Bubb, Quenton R., Plummer, Ashlee M., Fleming, Karen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031210/
https://www.ncbi.nlm.nih.gov/pubmed/36775935
http://dx.doi.org/10.1002/pro.4592