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TSG‐6 inhibits hypertrophic scar fibroblast proliferation by regulating IRE1α/TRAF2/NF‐κB signalling

TNF‐stimulated gene (TSG‐6) was reported to suppress hypertrophic scar (HS) formation in a rabbit ear model, and the overexpression of TSG‐6 in human HS fibroblasts (HSFs) was found to induce their apoptotic death. The molecular basis for these findings, however, remains to be clarified. HSFs were s...

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Detalles Bibliográficos
Autores principales: Ma, Li, Hua, Lei, Yu, Wenyuan, Ke, Li, Li, Liang‐yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031217/
https://www.ncbi.nlm.nih.gov/pubmed/36056472
http://dx.doi.org/10.1111/iwj.13950