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Demonstration of Safety in Wild Type Mice of npFOXF1, a Novel Nanoparticle-Based Gene Therapy for Alveolar Capillary Dysplasia with Misaligned Pulmonary Veins

INTRODUCTION: Alveolar Capillary Dysplasia with Misaligned Pulmonary Veins (ACDMPV) is a fatal congenital disease resulting from a pulmonary vascular endothelial deficiency of FOXF1, producing abnormal morphogenesis of alveolar capillaries, malpositioned pulmonary veins and disordered development of...

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Detalles Bibliográficos
Autores principales: Kohram, Fatemeh, Deng, Zicheng, Zhang, Yufang, Al Reza, Abid, Li, Enhong, Kolesnichenko, Olena A, Shukla, Samriddhi, Ustiyan, Vladimir, Gomez-Arroyo, Jose, Acharya, Anusha, Shi, Donglu, Kalinichenko, Vladimir V, Kenny, Alan P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031269/
https://www.ncbi.nlm.nih.gov/pubmed/36969329
http://dx.doi.org/10.2147/BTT.S400006