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Demonstration of Safety in Wild Type Mice of npFOXF1, a Novel Nanoparticle-Based Gene Therapy for Alveolar Capillary Dysplasia with Misaligned Pulmonary Veins
INTRODUCTION: Alveolar Capillary Dysplasia with Misaligned Pulmonary Veins (ACDMPV) is a fatal congenital disease resulting from a pulmonary vascular endothelial deficiency of FOXF1, producing abnormal morphogenesis of alveolar capillaries, malpositioned pulmonary veins and disordered development of...
Autores principales: | Kohram, Fatemeh, Deng, Zicheng, Zhang, Yufang, Al Reza, Abid, Li, Enhong, Kolesnichenko, Olena A, Shukla, Samriddhi, Ustiyan, Vladimir, Gomez-Arroyo, Jose, Acharya, Anusha, Shi, Donglu, Kalinichenko, Vladimir V, Kenny, Alan P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031269/ https://www.ncbi.nlm.nih.gov/pubmed/36969329 http://dx.doi.org/10.2147/BTT.S400006 |
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