In silico discovery of small molecules for efficient stem cell differentiation into definitive endoderm

Improving methods for human embryonic stem cell differentiation represents a challenge in modern regenerative medicine research. Using drug repurposing approaches, we discover small molecules that regulate the formation of definitive endoderm. Among them are inhibitors of known processes involved in...

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Detalles Bibliográficos
Autores principales: Novakovsky, Gherman, Sasaki, Shugo, Fornes, Oriol, Omur, Meltem E., Huang, Helen, Bayly, Carmen L., Zhang, Dahai, Lim, Nathaniel, Cherkasov, Artem, Pavlidis, Paul, Mostafavi, Sara, Lynn, Francis C., Wasserman, Wyeth W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031281/
https://www.ncbi.nlm.nih.gov/pubmed/36801003
http://dx.doi.org/10.1016/j.stemcr.2023.01.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031281/
https://www.ncbi.nlm.nih.gov/pubmed/36801003
http://dx.doi.org/10.1016/j.stemcr.2023.01.008

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