Excitotoxic glutamate levels drive spinal cord ependymal stem cell proliferation and fate specification through CP-AMPAR signaling

The adult spinal cord contains a population of ependymal-derived neural stem/progenitor cells (epNSPCs) that are normally quiescent, but are activated to proliferate, differentiate, and migrate after spinal cord injury. The mechanisms that regulate their response to injury cues, however, remain unkn...

Descripción completa

Detalles Bibliográficos
Autores principales: Hachem, Laureen D., Hong, James, Velumian, Alexander, Mothe, Andrea J., Tator, Charles H., Fehlings, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031285/
https://www.ncbi.nlm.nih.gov/pubmed/36764296
http://dx.doi.org/10.1016/j.stemcr.2023.01.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031285/
https://www.ncbi.nlm.nih.gov/pubmed/36764296
http://dx.doi.org/10.1016/j.stemcr.2023.01.005

Ejemplares similares